PREVENTIVE TREATMENT FOR PEANUT ALLERGIES SUCCEEDS IN STUDY

 By MARILYNN MARCHIONE

The first treatment to help prevent serious allergic reactions to peanuts may be on the way. A company said Tuesday that its daily capsules of peanut flour helped sensitize children to nuts in a major study.
Millions of children have peanut allergies, and some may have life-threatening reactions if accidentally exposed to them. Doctors have been testing daily doses of peanut flour, contained in a capsule and sprinkled over food, as a way to prevent that.
California-based Aimmune (AIM-yoon) Therapeutics said 67 percent of kids who had its treatment were able to tolerate the equivalent of roughly two peanuts at the end of the study, compared to only 4 percent of others given a dummy powder.
The study involved nearly 500 kids ages 4 to 17 with severe peanut allergies. They were given either capsules of peanut flour or a dummy powder in gradually increasing amounts for six months, then continued on that final level for another six months. Neither the participants nor their doctors knew who was getting what until the study ended.
About 20 percent of kids getting the peanut powder dropped out of the study, 12 percent due to reactions or other problems.
The results have not yet been reviewed by independent experts, but will be presented at a medical meeting next month.
The company plans to file for U.S. Food and Drug Administration approval for the treatment by the end of this year, and for approval in Europe early next year.
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Marilynn Marchione can be followed on Twitter: @MMarchioneAP